There should not be any risk as long as you hyper anywhere between (-500, -500) and (500, 500). There should be no possible system where simply entering would subject you to danger. However, there could be a system (such as (0, 0)), where there are many black holes in the system, and moving from the entrance point could subject you to the danger of being killed.
It should be impossible to hyper outside of the galaxy. Any method that allows you to do so is a bug and you'll have to get the admins to move you back into the galaxy.