It depends. Combat builds require more skill points than any other build within the Combine so it can be difficult, especially early on. In my opinion the most important skill for ground combat is Infantry Command since you gain more offense and defense from this skill than any other skill.
The amount of skill points that you wish to spend on personal skills, or skills that only affect your survivability and damage, depends entirely on how much you like combat. If you devote a lot of your time toward hunting and grinding experience I would recommend Medical Treatment with Healing Sticks.
The most important personal skills are Dexterity, Dodge and Strength. Dexterity allows you to hit enemies and is generally more useful than any of the specific weapon skills. Specific weapon skills should only be taken after you have upgraded your more important skills.
You should increase your Dodge skill to 4 or 5, any less and it is not very useful. The reason is that most NPC's in PvP or PvE will have an accuracy of 4 to 5 which allows you to have a 40% to 50% chance of avoiding damage entirely. Higher Strength, which means more health points, increases the effectiveness of the Dodge skill.
The equipment you use depends on what you wish to hunt. At the moment the A280 is the one of the least common weapon in bandit fitouts and is the only weapon that can attack at a range of 9. Since bandits do not move or attack, unless you attack them, this will allow you to defeat them without taking damage yourself. This will change when combat is implemented and activated. I personally use a DLT-20a and an A280 because it covers all ranges between 2 and 10. I would also recommend a Sprint-class rescue craft because it is one of the better ships for hunting.
Sensors. Biological Sensor Packs allow you to find any organic enemy which means all bandits, except the the occasional droid, and creatures. What you do is hire 12 scouts and equip each of them with macrobinoculars and a Biological Sensor Pack. Then place 3 scouts on each terrain square; you might have to move them around a little to find the correct places to cover the entire area. If you are equipped with a sensor pack you can see everything your scouts see and allows you to cover 4 terrain squares.
If you want to farm experience points and have a decent Medical Treatment skill then purchase a mace or staff from the NPC shop and healing sticks from a medical faction. Find a creature that can do a lot of damage and spend your time attacking and healing. You should not have NPC's with you if you do this or when combat is fully implemented. This is just the basics so there is a lot of more specific information I am sure I did not mention.